6FDB

Positively supercharged variant of the computationally designed cage protein O3-33

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MCP Type
Metabolosome (B12-dependent)
MCP Classification
Semi-Synthetic from PDU MCP (PduT)
Protein Type and Topology
BMC-T
Observed Assembly Form
Cage
Pfam
PF00936 [96-173]/PF00936 [4-76]



Structure Information

PDB ID 6FDB [PDB]
Structure Title Positively supercharged variant of the computationally designed cage protein O3-33
Resolution 3.62 Å
Method X-RAY DIFFRACTION
Length 184 Amino Acids
Molecular Weight 19,150 Da
Organism Salmonella enterica (Salmonella choleraesuis)
UniProt ID A0A0M0QF47
Gene Name pduT
Structure Authors Edwardson, T. Mori, T. Hilvert, D.



Publication Information

Title Rational Engineering of a Designed Protein Cage for siRNA Delivery.
Authors Edwardson, T.G.W., Mori, T., Hilvert, D.
Publication Year 2018
PubMed ID 30091604